Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB

Autor: Lee A. Rettberg, Jarett Wilcoxen, Andrew J. Jasniewski, Chi Chung Lee, Kazuki Tanifuji, Yilin Hu, R. David Britt, Markus W. Ribbe
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-15627-9
Popis: NifB is a radical SAM enzyme involved in the biosynthesis of the Mo-nitrogenase cofactor, which is responsible for the ambient conversion of N2 to NH3. Here, the authors identify and uncover the function of a His43 residue as an essential nitrogen ligand of NifB in cofactor biosynthesis.
Databáze: Directory of Open Access Journals