Methotrexate toxicity complicating a case of rheumatoid arthritis associated Interstitial Lung Disease: Lessons to learn

Autor: H. Ikrou, M. Salek, S. Boustani, W. Bouissar, S. Wakrim, S. Abdala, H. Serhane
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Radiology Case Reports, Vol 19, Iss 6, Pp 2218-2223 (2024)
Druh dokumentu: article
ISSN: 1930-0433
DOI: 10.1016/j.radcr.2024.02.036
Popis: Rheumatoid arthritis (RA) is one of the most common types of autoimmune arthritis. It can also involve other organs, including vascular structures, and lungs which are affected in 60% to 80% of cases. Other complications may present as airway infections and drug related pulmonary toxicity. We present the case of 75-year-old male patient of North African decent that was hospitalized initially for chronic dyspnea associated with other systemic manifestations, and in whom we confirmed the diagnosis of Rheumatoid arthritis associated interstitial lung disease. The patient was treated with methotrexate (MTX) and later on, he developed a fatal case of methotrexate related pulmonary toxicity.
Databáze: Directory of Open Access Journals