Simultaneous quantification of five major active components in capsules of the traditional Chinese medicine âShu-Jin-Zhi-Tongâ by high performance liquid chromatography

Autor: Xing-Xin Yang, Xiao-Xia Zhang, Rui-Miao Chang, Yan-Wei Wang, Xiao-Ni Li
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Journal of Pharmaceutical Analysis, Vol 1, Iss 4, Pp 284-290 (2011)
Druh dokumentu: article
ISSN: 2095-1779
DOI: 10.1016/j.jpha.2011.08.002
Popis: A simple and reliable high performance liquid chromatography (HPLC) method has been developed for the simultaneous quantification of five major bioactive components in âShu-Jin-Zhi-Tongâ capsules (SJZTC), for the purposes of quality control of this commonly prescribed traditional Chinese medicine. Under the optimum conditions, excellent separation was achieved, and the assay was fully validated in terms of linearity, precision, repeatability, stability and accuracy. The validated method was applied successfully to the determination of the five compounds in SJZTC samples from different production batches. The HPLC method can be used as a valid analytical method to evaluate the intrinsic quality of SJZTC. Keywords: High performance liquid chromatography, Quality control, âShu-Jin-Zhi-Tongâ capsules, Traditional Chinese medicine
Databáze: Directory of Open Access Journals