Statistical association of rs2243250 polymorphism of IL4 gene and hemorrhagic stroke in Brazilian population

Autor:	Ângelo M. Rolim, Felipe S. A. Borges, Aline R. Barros, Jonathan D. Lima, Fabiana B. A. Silva, Hélia Carla de Souza, Daniel O. Freire, Luzitano B. Ferreira, Izabel Cristina R. Silva
Jazyk:	angličtina
Předmět:	interleucina-4 polimorfismo de nucleótide simple accidente cerebrovascular hemorragias intracraneales aneurisma intracraneal Pathology RB1-214
Zdroj:	Jornal Brasileiro de Patologia e Medicina Laboratorial, Vol 56
Druh dokumentu:	article
ISSN:	1676-2444 1678-4774
DOI:	10.5935/1676-2444.20200031
Popis:	ABSTRACT Interleukin-4 (IL-4) has great significance in inflammatory processes in cases of stroke, since it is able to polarize microglia to the antiinflammatory phenotype called M2. This study analyzed if the variation between TT genotype and the other genotypes (CT and CC), in -589 (rs2243250) polymorphism of IL4 gene, has association with the prognosis of hemorrhagic stroke (HS) and with clinical aspects which are risk factors for cerebrovascular diseases. The result of this study shows that there is no statistical association of the IL4 polymorphism with either prognosis or clinical aspects in HS patients.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/8feb708e6c1d4a82aef03f3473de19af Zobrazit plný text záznamu View record in DOAJ