| Autor: |
Huang Furong, Feng Chengtian, Cao Shiyu, Jiang Yongdong |
| Jazyk: |
čínština |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Xin yixue, Vol 54, Iss 12, Pp 855-859 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
0253-9802 |
| DOI: |
10.3969/j.issn.0253-9802.2023.12.003 |
| Popis: |
Tumor endothelial marker 8 （TEM8） is a highly-conserved single-shot transmembrane glycoprotein. TEM8 is a special member of the tumor endothelial marker family，which was first discovered in colon cancer tissues. Studies have shown that TEM8 is specifically expressed in a variety of malignant tumor cells and tumor vascular endothelia，and participates in malignant biological behaviors，such as tumor proliferation and angiogenesis，which is a biomarker for early diagnosis and prognosis of some malignant tumors，and can be used as a new target for the treatment of malignant tumors. This article will introduce the mechanism of TEM8 in malignant tumors and its clinical application progress. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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