Azole resistance of Malassezia pachydermatis causing treatment failure in a dog

Autor: Martina Angileri, Mario Pasquetti, Michela De Lucia, Andrea Peano
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Medical Mycology Case Reports, Vol 23, Iss , Pp 58-61 (2019)
Druh dokumentu: article
ISSN: 2211-7539
DOI: 10.1016/j.mmcr.2018.12.004
Popis: A 5-year-old neutered female toy Poodle chronically treated with systemic and topical azoles to control recurrent Malassezia dermatitis/otitis was presented because of the loss of treatment efficacy. Minimum Inhibitory Concentrations (MICs) obtained in vitro for various azoles (especially itraconazole and ketoconazole) against Malassezia strains isolated from the dog were increased by several-fold compared with MICs obtained for control isolates. These results reinforced the assumption based on clinical observation, i.e. the development of azole resistance Keywords: Malassezia pachydermatis, Dog, Resistance, Azoles
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