Acute Liver Failure Occurring during the First Trimester of Pregnancy Successfully Treated with Living Donor Liver Transplantation

Autor: Naoya Kanogawa, Tatsuo Kanda, Masayuki Ohtsuka, Masato Nakamura, Tatsuo Miyamura, Shin Yasui, Makoto Arai, Hitoshi Maruyama, Keiichi Fujiwara, Makio Shozu, Shigeto Oda, Masaru Miyazaki, Osamu Yokosuka
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Case Reports in Transplantation, Vol 2013 (2013)
Druh dokumentu: article
ISSN: 2090-6943
2090-6951
DOI: 10.1155/2013/309545
Popis: Acute liver failure (ALF) during pregnancy remains difficult to treat, and despite advances in treatment, liver transplantation must be selected as treatment option in certain cases. We report a 30-year-old woman with ALF of unknown etiology, occurring during the first trimester of pregnancy. Her condition was complicated by consciousness disturbance and coagulopathy due to ALF, but she was successfully treated with living donor liver transplantation 7 days after dilatation and curettage. At 9-month followup, she was in good medical condition. Liver transplantation has been reported as one of the treatment options for ALF during pregnancy with the prognosis varying depending on the trimester, from living donor or deceased donor liver transplantation. Of importance is that clinicians always think of emergent liver transplantation as a therapeutic option in ALF even in the first trimester of pregnancy.
Databáze: Directory of Open Access Journals