Fecal calprotectin Level in patients with IBD and noninflammatory disease of colon: a study in Babol, Northern, Iran

Autor: Majid Sharbatdaran, Amin Halakou, Mehrdad Kashifard, Ali Bijani, Alireza Firozjaei, Akram Hossaini, Sepideh Siadati
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Caspian Journal of Internal Medicine, Vol 9, Iss 1, Pp 60-64 (2018)
Druh dokumentu: article
ISSN: 2008-6164
2008-6172
Popis: Background: Inflammatory bowel disease (IBD) is a chronic disease with a relapsing course of inflammation in the digestive system. Endoscopy and histopathology are the golden standard methods for detection and assessment of IBD. A distinct increase of fecal calprotectin level can be a useful marker for the diagnosis of IBD. The aim of this study was to evaluate the fecal calprotectin level in patients with IBD and without inflammatory diseases of the colon. Methods: Calprotectin levels of patients referred to the Ayatollah Rouhani Hospital of Babol, northern Iran with clinical symptoms of colon disease were evaluated. After a week, colonoscopy and biopsy were performed on all patients and they were divided into two groups. The first group included patients with confirmed IBD and the second group included patients with diseases other than IBD, patients with IBS and healthy persons. Then the measured fecal calprotectin level was compared between the two groups before colonoscopy. Results: We observed correlation between calprotection in these two groups (p
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