The features of pathophisiology Helicobacter pilory associated ulceractive disease from the Khakasses
| Autor: | Ye. S. Ageyeva, O. V. Shtygasheva, N. V. Ryazntseva |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2009 |
| Předmět: | |
| Zdroj: | Бюллетень сибирской медицины, Vol 8, Iss 4, Pp 5-9 (2009) |
| Druh dokumentu: | article |
| ISSN: | 1682-0363 1819-3684 |
| DOI: | 10.20538/1682-0363-2009-4-5-9 |
| Popis: | Peculiarities of pathogene sis of Helicobacter pylori (HP)-associated gastric ulcer (GU) in Khakas se s are investigated. It is found that, in con - trast to Caucasian s, the activation of the Т-cell and humoral parts of the immune response in Mongoloids with GU is accompanied by the high con - tent of CD4 +- and CD20 +-lympho cytes in the muscou s coat of stomach. Changes revealed in the peripheral blood in GU patients were character - ized by a decrease in the magnitude of CD4 +- and CD8 +-lympho cyte subpopulations compared to patients with chronic gastritis. The detected pos - itive correlation between the АА-251 genotype of interleukin-8 and the risk of GU development in Khakssses indicated in favor of the existence of immuno-genetic regularities of GU development. The reasonability of determining population risk and protective genotypes of development of HРassociated GU in Khakasses is discussed. |
| Databáze: | Directory of Open Access Journals |
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