Efficacy of hypobaric hypoxia in the treatment of arterial hypertension in postmenopausal women

Autor: Aleksey Nikolaevich Tin'kov, Ol'ga Dmitrievna Konstantinova, Svetlana Konstantinovna Kshnyaseva, A N Tinkov, O D Konstantinova, S K Kshnyaseva
Jazyk: ruština
Rok vydání: 2011
Předmět:
Zdroj: Терапевтический архив, Vol 83, Iss 12, Pp 16-19 (2011)
Druh dokumentu: article
ISSN: 0040-3660
2309-5342
Popis: Aim. To assess efficacy of adaptation to periodic hypobaric hypoxia (PHH) in the treatment of postmenopausal women with arterial hypertension (AH). Material and methods. The method of adaptation to PHH in the pressure chamber Ural-1 (22 three-hour daily sessions, pressure 460 mmHg) was used in 46 postmenopausal AH women (mean age 53,8 ± 3,9 years). The method was assessed for effects on blood pressure (BP), symptoms of menopausal syndrome, body mass, levels of some hormones, lipid and carbohydrate metabolism. Results. Adaptation to PHH reduced systolic pressure by 13,9%, diastolic one - by 8,2%, the levels of folliculestimulating and luteinising hormones by 26,8 and 21,5%, respectively, cholesterol - by 14,7, glucose - by 21,3, insulin - 20,2%; estradiol and dehydroepiandrosteron sulphate concentrations rose by 19,3 and 15,2%, respectively. Conclusion. Adaptation to PHH produced an antihypertensive effect and a positive trend in clinicometabolic indices in AH women in postmenopause.
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