Tumor Necrosis Factor-Alpha and Mast Cells: Revisited Study

Autor: A. Saggini, D. Tripodi, G. Maccauro, M.L. Castellani, A. Anogeianaki, S. Teté, P. Felaco, M.A. De Luths, R. Galzio, M. Fulcheri, T.C. Theoharides, A. Caraffa, P. Antinolfi, M. Felaco, F. Conti, G. Neri, F. Pandolfi, E. Tomato, Y.B. Shaik-Dasthagirisaheb
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: European Journal of Inflammation, Vol 9 (2011)
Druh dokumentu: article
ISSN: 1721-727X
1721727X
DOI: 10.1177/1721727X1100900103
Popis: Mast cells reside in connective tissues and are widely recognized as effector cells important in innate and acquired immunity. These cells are the only ones capable of storing preformed TNFα in their cytoplasmatic granules and release upon activation. TNF-alpha is a potent multifunctional cytokine involved in autoimmune diseases, cancer, allergy, and acute and chronic inflammation. In this study, we revisit the interrelationship between TNFα and mast cells.
Databáze: Directory of Open Access Journals