Convalescent-Phase Sera and Vaccine-Elicited Antibodies Largely Maintain Neutralizing Titer against Global SARS-CoV-2 Variant Spikes

Autor: Takuya Tada, Belinda M. Dcosta, Marie I. Samanovic, Ramin S. Herati, Amber Cornelius, Hao Zhou, Ada Vaill, Wes Kazmierski, Mark J. Mulligan, Nathaniel R. Landau
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: mBio, Vol 12, Iss 3 (2021)
Druh dokumentu: article
ISSN: 2150-7511
DOI: 10.1128/mBio.00696-21
Popis: The rapid evolution of SARS-CoV-2 variants has raised concerns with regard to their potential to escape from vaccine-elicited antibodies and anti-spike protein monoclonal antibodies. We report here on an analysis of sera from recovered patients and vaccinated individuals and on neutralization by Regeneron therapeutic monoclonal antibodies.
Databáze: Directory of Open Access Journals