Autor: |
Mozhgan Ahmadi, Asieh Abbassi Daloii, Samira Salehi Kiasari |
Jazyk: |
perština |
Rok vydání: |
2020 |
Předmět: |
|
Zdroj: |
Complementary Medicine Journal of Faculty of Nursing and Midwifery, Vol 9, Iss 4, Pp 3890-3901 (2020) |
Druh dokumentu: |
article |
ISSN: |
2228-7094 |
Popis: |
Objective: This study aimed to compare the response of liver tissue BAX and BCL-2 gene expression to aerobic training with L-carnitine supplementation in rats intoxicated by Boldenone. Methods: In this experimental study, 30 male Wistar rats, aged 12 weeks (weight 195±7.94 g) were randomly divided into five groups: Control, no-treatment, boldenone (5 mg/kg), L-carnitine (100 mg/kg) and aerobic training- L-carnitine. The moderate endurance intensity training program (50%-55% of maximal oxygen consumption) performed for 6 weeks and 5 times a week. Injection once a week in the quadriceps and hamstring was conducted in-depth. After anesthesia, an autopsy was performed, and the liver Isolated. The hepatic apoptosis gene expression in the samples was measured by Real-Time PCR. Data were analyzed by 1-way ANOVA and post hoc Scheffe at the significant level P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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