| Autor: |
Patrícia Pita Lobo, Susana Pinto, Luz Rocha, Sofia Reimão, Mamede de Carvalho |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Case Reports in Neurology, Vol 5, Iss 1, Pp 47-51 (2013) |
| Druh dokumentu: |
article |
| ISSN: |
1662-680X |
| DOI: |
10.1159/000349895 |
| Popis: |
Introduction: Cognitive and behavioral impairments are considered to occur frequently in amyotrophic lateral sclerosis/motor neuron disease (MND). Rarely, apraxia has been reported in MND. Orofacial, or buccofacial, apraxia is characterized by a loss of voluntary control of facial, lingual, pharyngeal and masticatory muscles in the presence of preserved reflexive and automatic functions of the same muscles. Methods: We report a patient with MND who presented with spastic dysarthria and asymmetric orofacial apraxia. She progressed to frontotemporal dementia (FTD). Results: Clinical and neurophysiological examinations were suggestive of bulbar-onset MND-FTD. Tractography showed a reduction of fractional anisotropy in the centrum semiovale, corona radiata, corticomedullary pathway and inferior aspect of the medulla; the changes were more severe on the left side. To our knowledge, this is the first report of an asymmetric presentation of an apraxic syndrome in MND-FTD. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
