Optical Temperature Control Unit and Convolutional Neural Network for Colorimetric Detection of Loop-Mediated Isothermal Amplification on a Lab-On-A-Disc Platform

Autor:	Da Ye Seul Lim, Moo-Jung Seo, Jae Chern Yoo
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	lab-on-a-disc loop-mediated isothermal amplification point-of-care testing hydroxy naphthol blue convolutional neural network Chemical technology TP1-1185
Zdroj:	Sensors, Vol 19, Iss 14, p 3207 (2019)
Druh dokumentu:	article
ISSN:	1424-8220
DOI:	10.3390/s19143207
Popis:	Lab-on-a-disc (LOD) has emerged as a promising candidate for a point-of-care testing (POCT) device because it can effectively integrate complex fluid manipulation steps using multiple layers of polymeric substrates. However, it is still highly challenging to design and fabricate temperature measurement and heating system in non-contact with the surface of LOD, which is a prerequisite to successful realization of DNA amplification especially with a rotatable disc. This study presents a Lab-on-a-disc (LOD)-based automatic loop-mediated isothermal amplification (LAMP) system, where a thermochromic coating (
Databáze:	Directory of Open Access Journals
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