Systemic Inflammatory Response Syndrome Secondary to Nitrofurantoin

Autor: Molly R. McGarry PharmD, Meredith W. Wagner MD, Barry M. Wall MD
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Investigative Medicine High Impact Case Reports, Vol 9 (2021)
Druh dokumentu: article
ISSN: 2324-7096
23247096
DOI: 10.1177/2324709620984610
Popis: Nitrofurantoin is considered optimal treatment for acute uncomplicated cystitis by the Infectious Diseases Society of America and is being increasingly recommended due to microbial resistance to sulfamethoxazole/trimethoprim and various fluoroquinolone antibiotics. Adverse effects of nitrofurantoin are generally considered mild, with gastrointestinal complaints being the most common. However, there have been isolated case reports describing a more severe systemic inflammatory response syndrome–like reaction, which leads to diagnostic challenges and treatment complications. We report the case of a patient with repeat episodes of systemic inflammatory response syndrome secondary to nitrofurantoin, which was initially attributed to recurrent urinary tract infections.
Databáze: Directory of Open Access Journals