Autor: |
Takashi Mizutani, Norio Umemoto, Toshio Taniguchi, Hideki Ishii, Yuri Hiramatsu, Koji Arata, Horagaito Takuya, Sho Inoue, Tsuyoshi Sugiura, Toru Asai, Michiharu Yamada, Toyoaki Murohara, Kiyokazu Shimizu |
Jazyk: |
angličtina |
Rok vydání: |
2018 |
Předmět: |
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Zdroj: |
Journal of Intensive Care, Vol 6, Iss 1, Pp 1-7 (2018) |
Druh dokumentu: |
article |
ISSN: |
2052-0492 |
DOI: |
10.1186/s40560-018-0302-z |
Popis: |
Abstract Background Serum lactate level can predict clinical outcomes in some critical cases. In the clinical setting, we noted that patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR) and with poor serum lactate improvement often do not recover from cardiopulmonary arrest. Therefore, we investigated the association between lactate clearance and in-hospital mortality in cardiac arrest patients undergoing ECPR. Methods Serum lactate levels were measured on admission and every hour after starting ECPR. Lactate clearance [(lactate at first measurement − lactate 6 h after)/lactate at first measurement × 100] was calculated 6 h after first serum lactate measurement. All patients who underwent ECPR were registered retrospectively using opt-out in our outpatient’s segment. Result In this retrospective study, 64 cases were evaluated, and they were classified into two groups according to lactate clearance: high-clearance group, > 65%; low-clearance group, ≤ 65%. Surviving discharge rate of high-clearance group (12 cases, 63%) is significantly higher than that of low-clearance group (11 cases, 24%) (p |
Databáze: |
Directory of Open Access Journals |
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