P6.19 GENDER DIFFERENCES OF ARTERIAL STIFFNESS AND CENTRAL BLOOD PRESSURE IN PATIENTS WITH ARTERIAL HYPERTENSION AND THE INFLUENCE OF MENOPAUSE

Autor: Valéria Costa-Hong, Henrique Muela, Allan Sales, Luiz Bortolotto
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Artery Research, Vol 12 (2015)
Druh dokumentu: article
ISSN: 1876-4401
DOI: 10.1016/j.artres.2015.10.303
Popis: Introduction: In general population women seems to have greater arterial stiffness and central blood pressure(BP), measured by augmentation index (AIx), than men, but in hypertension this condition is poorly studied. Objectives: To evaluate differences of central BP and arterial stiffness between men and women with arterial hypertension and the influence of postmenopausal status. Methods: We studied 128 subjects with stage 1–3 arterial hypertension, mean age 51.1±11 years, 48% males, BP = 141±24/87±13 mmHg, hypertension duration 10.1±8 years. Noninvasive central aortic BP and wave form characteristics (Alx and AIx corrected by heart rate of 75 bpm – Alx75) were synthesized from radial arterial pressure waves (applanation tonometry) by SphygmoCor®. Brachial BP was obtained by an automatic device(OMRON®). Results: Brachial systolic BP was higher (145±26 vs. 136±20 mmHg, p=0.04) and, weight (76.2±14 vs. 86.4±13.2, p
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