Biochemical and histopathological changes in sheep fed different detoxified karanj (Pongamia glabra) seed cake as partial protein supplements

Autor: Nira Manik Soren, Anil K. Sharma, Vadali R.B. Sastry
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Animal Nutrition, Vol 3, Iss 2, Pp 164-170 (2017)
Druh dokumentu: article
ISSN: 2405-6545
DOI: 10.1016/j.aninu.2017.04.002
Popis: The study investigated the long-term effect of feeding processed solvent extracted karanj (Pongamia glabra) cake (SKC) on gross pathology and histopathological changes in some vital organs, and on the activities of serum enzymes in Jalauni lambs. Twenty-four male lambs were divided into 4 groups and allotted randomly to a soybean meal (SBM) based control (CON) and 3 treatment groups receiving concentrate mixtures, containing water washed (WW), 2.5% lime (LM) and 0.4% binder (BN) treated SKC replacing 50% nitrogen of SBM to meet the protein requirements. Blood was collected after 150 days from all the lambs and serum activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and lactate dehydrogenase (LDH) were assayed. All lambs were sacrificed after 196 days, and vital organs screened for gross pathological lesions. The representative tissues of liver, intestine, parathyroid gland, testis, and epididymis were sampled, preserved in 10% formalin and processed to examine histopathological changes by staining with haematoxylin and eosin (HE). The serum enzyme activities of AST and ALT were similar in the treatments, but the activity of LDH was higher (P
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