The evaluation of the results of nephrobiopsies in patients with lupus nephritis
Autor: | N.F. Soroka, M.V. Dmitrieva, V.A. Rabtsevich |
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Jazyk: | English<br />Russian |
Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Вестник Витебского государственного медицинского университета, Vol 22, Iss 2, Pp 35-46 (2023) |
Druh dokumentu: | article |
ISSN: | 2312-4156 1607-9906 |
DOI: | 10.22263/2312-4156.2023.2.35 |
Popis: | Lupus nephritis is characterized by a variety of clinical and morphological manifestations. Histological changes in the renal tissue often determine the course and prognosis of the disease. The performance of nephrobiopsy provides an important information about the morphological changes in the kidneys and their severity. Objectives. To evaluate histological changes in the renal tissue determined by kidney biopsy in patients with systemic lupus erythematosus. Material and methods. We analyzed 191 specimens of renal biopsy from 161 patients with systemic lupus erythematosus. Examination was conducted using light and immunofluorescent microscopy. Results. The most significant signs of the inflammatory process and sclerotic changes in the renal tissue were revealed in class IV: the presence of crescents (p |
Databáze: | Directory of Open Access Journals |
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