Is periodontal infection a risk factor for thromboembolic disease? A systematic review

Autor: Oinam Monica Devi, Jyoti Gupta, Gurparkash Singh Chahal, Ashish Jain
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Indian Society of Periodontology, Vol 27, Iss 3, Pp 238-250 (2023)
Druh dokumentu: article
ISSN: 0972-124X
DOI: 10.4103/jisp.jisp_576_21
Popis: Background: Venous thromboembolism (VTE) is a rising major health problem comprising pulmonary embolism (PE) and deep vein thrombosis. It is of concern due to premature mortality, increased morbidity, and associated healthcare costs and hospitalization. Periodontitis can increase the risk of VTE by way of systemic inflammation induced by infection that can contribute to hypercoagulability and platelet aggregation. This systematic review aims to synthesize all the evidence concerning periodontal infection as a risk factor for thromboembolic disease. Materials and Methods: A search for articles published from 1967 till December 2020 was conducted in the PubMed (MEDLINE), Scopus, and EMBASE data bases. Results: Five hundred and five articles were retrieved after running search strategies in PubMed, Scopus, and EMBASE search databases. Based on the inclusion criteria, three clinical studies, two case series, and ten case reports were included for qualitative analysis. The presence of periodontal disease was reported to influence the occurrence of venous thromboembolic disease with a statistical significance of
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