| Autor: |
Simrat Kaur, MD, Gursharan Singh Samra, MD, Manpreet Kaur, MD, Nabin K. Shrestha, MD, Steven Gordon, MD, E. Murat Tuzcu, MD, Samir Kapadia, MD, Amar Krishnaswamy, MD, Grant W. Reed, MD, MSc, Rishi Puri, MD, PhD, Lars G. Svensson, MD, PhD, Wael A. Jaber, MD, Brian P. Griffin, MD, Bo Xu, MD |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Structural Heart, Vol 6, Iss 1, Pp 100005- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2474-8706 |
| DOI: |
10.1016/j.shj.2022.100005 |
| Popis: |
Background: Transcatheter aortic valve replacement–associated infective endocarditis (TAVR-IE) is a relatively rare complication of TAVR. Little is known about the characteristics of early, intermediate, and late-onset TAVR-IE. Methods: We studied the risk factors, microbiological patterns, and diagnostic and treatment strategies in patients with early (1 year) TAVR-IE. Results: Ten out of 494 definite cases of prosthetic valve IE between 2007 and 2019 were confirmed to have TAVR-IE from the IE registry at our center. The mean age was 78.1 ± 13.7 years, with 50% being female. The mean Society of Thoracic Surgeons risk score was 7.8 ± 5.7. Most (60%) TAVR-IE cases had an intermediate onset, with Staphylococcus aureus being the most common organism (66.6%). 18-fluorodeoxyglucose positron emission tomography aided in diagnosis of TAVR-IE in 20% of cases. Mortality due to IE was observed in 40% of cases. Most of the patients underwent conservative management, and 37.5% survived over a mean follow-up of 709 ± 453 days. Two patients underwent surgery, of whom one died on day 30 postoperatively from sepsis. Mortality due to IE occurred in 25% of cases in the early and intermediate-onset groups, while there was 100% mortality in the late-onset group. Conclusions: In a single-center cohort, most TAVR-IE cases had an intermediate onset, with Staphylococcus aureus being the most common organism. Understanding timing of TAVR-IE may have important prognostic implications. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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