UDP-Glucuronosyltransferase Promoter Polymorphism in Iranian Neonates with Idiopathic Hyperbilirubinemia

Autor:	Mahbod Kaveh, Tahereh Esmailnia, Fatemeh Nayeri, Firoozeh Nili, Fatemeh Davari Tanha, Mahsa Ghajarzdeh
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Idiopathic Hyperbilirubinemia Neonate UDP-glucuronosyltransferase gene Medicine (General) R5-920
Zdroj:	Acta Medica Iranica, Vol 51, Iss 11 (2013)
Druh dokumentu:	article
ISSN:	0044-6025 1735-9694
Popis:	To determine the association between polymorphism of UGT1A1 gene and idiopathic hyperbilirubinemia in Iranian neonates. Fifty neonates with idiopathic hyperbilirubinemia and Serum total bilirubin (STB) more that 15mg/dl and 50 neonates with idiopathic hyperbilirubinemia and Serum total bilirubin (STB) less than 15mg/dl enrolled in this study. Thymine-adenine (TA) repeats in the promoter region of UGT1A1 gene investigated by means of polymerase- chain reaction (PCR) DNA sequencing. Demographic characteristics did not differ significantly between groups while STB was higher in case group (17.5±1.9 vs. 10.4±1.8, p value
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/8f1b430561fb486083fa6562e53ed3b4 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF