Dedifferentiation of esophageal progenitors in metaplasia and cancer

Autor: Alizée Vercauteren Drubbel, Benjamin Beck
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Molecular & Cellular Oncology, Vol 8, Iss 6 (2021)
Druh dokumentu: article
ISSN: 2372-3556
23723556
DOI: 10.1080/23723556.2021.1991758
Popis: Barrett syndrome is a squamo-columnar metaplasia increasing the risk of developing esophageal adenocarcinoma. Recently, we showed that esophageal cells can transdifferentiate into undifferentiated columnar cells in vivo. Here, we discuss about the potential of these cells to be a reservoir for intestinal metaplasia and/or esophageal adenocarcinoma.
Databáze: Directory of Open Access Journals
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