Role of 18F-FDG PET/CT for detection of recurrence and metastases in renal cell carcinoma—are we underusing PET/CT?
| Autor: | Melvika Pereira, Chirag B. Punatar, Natasha Singh, Sharad N. Sagade |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Diagnostic and Interventional Radiology, Vol 28, Iss 5, Pp 498-502 (2022) |
| Druh dokumentu: | article |
| ISSN: | 1305-3825 1305-3612 |
| DOI: | 10.5152/dir.2022.21096 |
| Popis: | PURPOSEThe aim of this study was to compare 18F-fluorodeoxyglucose positron emission tomography– computed tomography (18F-FDG PET/CT) scan with computed tomography (CT) scan for detecting recurrence and metastasis in renal cell carcinoma patients.METHODSThis retrospective study included patients from October 2013 to April 2017. Contrast-enhanced CT and PET/CT scans were compared and correlated with histopathology or/and follow-up studies.RESULTSSeventy-six patients, 60 males, were included. Lesions included primary renal, recurrent renal fossa lesions, lymph nodes, and distant metastatic lesions. Of 176 malignant lesions, CT detected 157 lesions; of which, 154 were true positive. Twenty-two false-negative lesions showed abnormal FDG uptake. CT scan had positive predictive value (PPV), negative predictive value (NPV), sensitivity, specificity, and accuracy of 98.0%, 37.1%, 87.5%, 81.2%, and 86.9%, respectively. All 176 lesions were PET/CT-positive. PET/CT had PPV, NPV, sensitivity, specificity, and accuracy of 100% each. The specificity and NPV of PET/CT were superior (P < .05).CONCLUSIONPET/CT appears more accurate than CT scan for detecting metastasis and recurrence in renal cell carcinoma patients. |
| Databáze: | Directory of Open Access Journals |
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