Looking at the periphery—new hypothesis to look for new targets for Alzheimer’s disease therapy

Autor: Jesús Avila, Mar Pérez, Marina Avila-Villanueva, Ismael Santa-María, Félix Hernández
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Exploration of Neuroprotective Therapy, Vol 3, Iss 3, Pp 151-163 (2023)
Druh dokumentu: article
ISSN: 2769-6510
DOI: 10.37349/ent.2023.00044
Popis: Currently, the predominant targets for the treatment of Alzheimer’s disease (AD) are the main components of the two pathological structures: senile plaques (composed of amyloid beta peptide aggregates) or neurofibrillary tangles (constructed of tau protein polymers). However, the existence of adequate disease modifiers based on such targets is discussed. In this special issue, it has been suggested to search for new possible targets for AD therapy. This contribution tries to analyze non-neuronal tissues (periphery) to identify potential factors (target) involved in the development of AD.
Databáze: Directory of Open Access Journals