Evaluation of factors related to overdose in patients with impaired consciousness who are transported by emergency medical services: an age-specific research

Autor: Kazuki Nagashima, Megumi Sumida, Shoichi Imanaka, Tatsuro Kuwabara, Ichiro Kaneko, Yasufumi Miyake, Nobuhiro Yasuno, Fumio Itagaki, Machiko Watanabe
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Pharmaceutical Health Care and Sciences, Vol 7, Iss 1, Pp 1-7 (2021)
Druh dokumentu: article
ISSN: 2055-0294
DOI: 10.1186/s40780-021-00217-8
Popis: Abstract Background Drug overdose accounts for most of the admissions to the emergency department. Prescription drugs, most of which are psychotropic medications, are often misused for drug overdose. The purpose of this study was to investigate the association between overdose in patients transported with disorders of consciousness and psychotropic medications administered prior to transport, so as to enable quick differentiation of drug overdose patients from patients with disorders of consciousness. Methods We evaluated 222 patients transported to the Advanced Critical Care Center of Teikyo University Hospital due to disorders of consciousness. The patients were categorized into two groups: overdose group (n = 128) and control group with other disorders of consciousness (n = 94). Logistic regression models were used to assess the association between disorders of consciousness due to drug overdose and psychotropic drugs prescribed before emergency transportation based on sex and age. Results According to multivariate logistic regression analysis, only female sex (odds ratio [OR] 4.54, 95% confidence interval [CI] 2.43–8.05, P
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