Infections and antimicrobial resistance in an adult intensive care unit in a Brazilian hospital and the influence of drug resistance on the thirty-day mortality among patients with bloodstream infections

Autor: Sebastiana Silva Sabino, Caio Augusto de Lima, Luiz Gustavo Machado, Paola Amaral de Campos, Astrídia Marília de Souza Fontes, Paulo Pinto Gontijo-Filho, Rosineide Marques Ribas
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Revista da Sociedade Brasileira de Medicina Tropical, Vol 53 (2020)
Druh dokumentu: article
ISSN: 1678-9849
0037-8682
DOI: 10.1590/0037-8682-0106-2019
Popis: Abstract INTRODUCTION: The present study aimed to determine the incidence of health care-associated infections (HCAIs) and identify the main resistant microorganisms in intensive care unit (ICU) patients in a Brazilian university hospital. METHODS: A retrospective cohort study was conducted in a Brazilian teaching hospital between 2012 and 2014. RESULTS: Overall, 81.2% of the infections were acquired in the ICU. The most common resistant pathogenic phenotypes in all-site and bloodstream infections were oxacillin-resistant coagulase-negative staphylococci and carbapenem-resistant Acinetobacter spp. (89.9% and 87.4%; 80.6% and 70.0%), respectively. CONCLUSIONS: There is an urgent need to focus on HCAIs in ICUs in Brazil.
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