| Autor: |
Alfredo Garcia Layana, Angelo Maria Minnella, Gerhard Garhöfer, Tariq Aslam, Frank G. Holz, Anita Leys, Rufino Silva, Cécile Delcourt, Eric Souied, Johanna M. Seddon |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Nutrients, Vol 9, Iss 10, p 1120 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2072-6643 |
| DOI: |
10.3390/nu9101120 |
| Popis: |
In recent years, the relationship between vitamin D and health has received growing attention from the scientific and medical communities. Vitamin D deficiencies have been repeatedly associated with various acute and chronic diseases, including age-related macular degeneration (AMD). Its active metabolite, 1α,25-dihydoxy vitamin D, acts as a modulator of cell proliferation, differentiation and apoptosis, and cumulative data from experimental and observational studies suggest that relatively a lower vitamin D status could be a potential risk factor for the development of early and/or late AMD. Herein, we made a narrative review of the mechanisms linking a potential role of vitamin D with the current concepts of AMD pathophysiology. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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