A rare case of multiple pituitary adenomas in an adolescent Cushing disease presenting as a vertebral compression fracture

Autor: Ji-Yeon Song, Sue-Jean Mun, Soon-Ki Sung, Jae-Yeon Hwang, Seung-Kug Baik, Jee Yeon Kim, Chong-Kun Cheon, Su-Young Kim, Yoo-Mi Kim
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Annals of Pediatric Endocrinology & Metabolism, Vol 22, Iss 3, Pp 197-202 (2017)
Druh dokumentu: article
ISSN: 2287-1012
2287-1292
DOI: 10.6065/apem.2017.22.3.197
Popis: Cushing disease in children and adolescents, especially with multiple pituitary adenomas (MPAs), is very rare. We report 17-year-old boy with MPAs. He presented with a vertebral compression fracture, weight gain, short stature, headache, and hypertension. On magnetic resonance imaging (MRI), only a left pituitary microadenoma was found. After surgery, transient clinical improvement was observed but headache and hypertension were observed again after 3 months later. Follow-up MRI showed a newly developed right pituitary microadenoma 6 months after the surgery. The need for careful clinical and radiographic follow-up should be emphasized in the search for potential MPAs in patients with persistent Cushing disease.
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