A rare case of multiple pituitary adenomas in an adolescent Cushing disease presenting as a vertebral compression fracture
Autor: | Ji-Yeon Song, Sue-Jean Mun, Soon-Ki Sung, Jae-Yeon Hwang, Seung-Kug Baik, Jee Yeon Kim, Chong-Kun Cheon, Su-Young Kim, Yoo-Mi Kim |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: | |
Zdroj: | Annals of Pediatric Endocrinology & Metabolism, Vol 22, Iss 3, Pp 197-202 (2017) |
Druh dokumentu: | article |
ISSN: | 2287-1012 2287-1292 |
DOI: | 10.6065/apem.2017.22.3.197 |
Popis: | Cushing disease in children and adolescents, especially with multiple pituitary adenomas (MPAs), is very rare. We report 17-year-old boy with MPAs. He presented with a vertebral compression fracture, weight gain, short stature, headache, and hypertension. On magnetic resonance imaging (MRI), only a left pituitary microadenoma was found. After surgery, transient clinical improvement was observed but headache and hypertension were observed again after 3 months later. Follow-up MRI showed a newly developed right pituitary microadenoma 6 months after the surgery. The need for careful clinical and radiographic follow-up should be emphasized in the search for potential MPAs in patients with persistent Cushing disease. |
Databáze: | Directory of Open Access Journals |
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