Texas Sour Orange Juice Used in Scaffolds for Tissue Engineering

Autor: Mandana Akia, Nataly Salinas, Cristobal Rodriguez, Robert Gilkerson, Luis Materon, Karen Lozano
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Membranes, Vol 8, Iss 3, p 38 (2018)
Druh dokumentu: article
ISSN: 2077-0375
DOI: 10.3390/membranes8030038
Popis: Fine fibers of polyhydroxybutyrate (PHB), a biopolymer, were developed via a centrifugal spinning technique. The developed fibers have an average diameter of 1.8 µm. Texas sour orange juice (SOJ) was applied as a natural antibacterial agent and infiltrated within the fibrous membranes. The antibacterial activity against common Gram-positive and Gram-negative bacteria (Staphylococcus aureus and Escherichia coli, respectively) was evaluated as well as cell adhesion and viability. The PHB/SOJ scaffolds showed antibacterial activity of up to 152% and 71% against S. aureus and E. coli, respectively. The cell studies revealed a suitable environment for cell growth and cell attachment. The outcome of this study opens up new opportunities for fabrication of fibrous materials for biomedical applications having multifunctional properties while using natural agents.
Databáze: Directory of Open Access Journals
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