Research progress of TLRs signaling pathway in pathogenesis of dry eye

Autor: Bao-Hua Li, Bo-Biao Ning, Yu-Jiao Wei, Xue-Feng Tang, Hui-Ling Ge, Fen-Yu Ma
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Guoji Yanke Zazhi, Vol 21, Iss 5, Pp 827-831 (2021)
Druh dokumentu: article
ISSN: 1672-5123
DOI: 10.3980/j.issn.1672-5123.2021.5.16
Popis: Toll-like receptors(TLRs)are bridges of innate and acquired immunity. With the deepening of the research on the pathogenesis of dry eye, the induction and regulation of TLRs and signaling pathways in the immune response to dry eye have attracted more and more attention. Current studies have shown that the regulation of TLRs and signaling pathways helps to reduce or prevent the inflammatory response process in dry eye, so the regulation and control of TLR signaling pathways in the treatment and prevention of dry eyes has important significance. In this paper, TLRs and their signaling pathways are summarized in the pathogenesis of dry eye, and the effects of different intervention methods on the TLR pathway of dry eye are discussed, and the future development prospects and problems are also discussed.
Databáze: Directory of Open Access Journals