One-on-one comparison between qCSI and NEWS scores for mortality risk assessment in patients with COVID-19
Autor: | Francisco Martín-Rodríguez, Ancor Sanz-García, Guillermo J. Ortega, Juan F. Delgado-Benito, Eduardo García Villena, Cristina Mazas Pérez-Oleaga, Raúl López-Izquierdo, Miguel A. Castro Villamor |
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Jazyk: | angličtina |
Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Annals of Medicine, Vol 54, Iss 1, Pp 646-654 (2022) |
Druh dokumentu: | article |
ISSN: | 0785-3890 1365-2060 07853890 |
DOI: | 10.1080/07853890.2022.2042590 |
Popis: | Objective To compare the predictive value of the quick COVID-19 Severity Index (qCSI) and the National Early Warning Score (NEWS) for 90-day mortality amongst COVID-19 patients. Methods Multicenter retrospective cohort study conducted in adult patients transferred by ambulance to an emergency department (ED) with suspected COVID-19 infection subsequently confirmed by a SARS-CoV-2 test (polymerase chain reaction). We collected epidemiological data, clinical covariates (respiratory rate, oxygen saturation, systolic blood pressure, heart rate, temperature, level of consciousness and use of supplemental oxygen) and hospital variables. The primary outcome was cumulative all-cause mortality during a 90-day follow-up, with mortality assessment monitoring time points at 1, 2, 7, 14, 30 and 90 days from ED attendance. Comparison of performances for 90-day mortality between both scores was carried out by univariate analysis. Results From March to November 2020, we included 2,961 SARS-CoV-2 positive patients (median age 79 years, IQR 66–88), with 49.2% females. The qCSI score provided an AUC ranging from 0.769 (1-day mortality) to 0.749 (90-day mortality), whereas AUCs for NEWS ranging from 0.825 for 1-day mortality to 0.777 for 90-day mortality. At all-time points studied, differences between both scores were statistically significant (p |
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