Omission of adjuvant radiotherapy following breast-conserving surgery for elderly women with early-stage pure mucinous breast carcinoma

Autor: San-Gang Wu, Feng-Yan Li, Jun Wang, Chen-Lu Lian, Juan Zhou, Zhen-Yu He
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Radiation Oncology, Vol 14, Iss 1, Pp 1-8 (2019)
Druh dokumentu: article
ISSN: 1748-717X
DOI: 10.1186/s13014-019-1394-x
Popis: Abstract Background We aimed to ascertain population-based practice patterns and survival outcomes of postoperative radiotherapy following breast conserving-surgery (BCS) in elderly women (aged ≥65 years) with early-stage pure mucinous breast carcinoma (PMBC). Methods Patients aged ≥65 years diagnosed with T1–2N0 and hormone receptor-positive PMBC between 1990 and 2010 were identified from the Surveillance, Epidemiology, and End Results database. Binomial logistic regression, Kaplan-Meier method, Multivariate Cox proportional hazards models, and propensity score matching (PSM) were used for statistical analysis. Results We enrolled 3416 patients, including 1225 (35.9%) and 2191 (64.1%) in the no-radiotherapy and radiotherapy cohorts, respectively. The percentage of patients receiving postoperative radiotherapy following BCS was significantly lower after 2004 (59.5% between 2004 and 2010), relative to that before 2004 (71.1% between 1990 and 2003; P
Databáze: Directory of Open Access Journals
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