| Autor: |
S. B. Chuelov, A. L. Rossina, V. F. Uchaikin |
| Jazyk: |
ruština |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Детские инфекции (Москва), Vol 16, Iss 3, Pp 32-40 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2072-8107 |
| DOI: |
10.22627/2072-8107-2017-16-3-32-40 |
| Popis: |
Treatment of chronic viral hepatitis is not a fully resolved problem, especially in children. There are no convincing criteria for recovery. The paper presents various schemes used for etiotropic therapy of viral hepatitis at the present stage — interferons and antiviral drugs. For the treatment of hepatitis B, synthetic nucleoside and nucleotide analogues are used as an antiviral therapy, in the case of hepatitis C — ribavirin and protease and polymerase inhibitors. In children, interferon therapy remains important with the use of domestic drugs, including rectal forms of interferon administration (VIFERON®). At the same time, active research is underway to study non-interferon regimens for the treatment of chronic viral hepatitis in pediatric practice, but so far the choice of drugs for non-interferon therapy is limited to individual drugs. With hepatitis B, it is a lamivudine, prescribed from 3 years (the reception of which is accompanied by frequent development of resistance) and — tenofovir (appointed from 12 years). With hepatitis C, ribavirin can be administered from 3 years. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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