Association of adiponectin 45T/G (rs2241766) and visfatin 4689G/T (rs2110385) gene polymorphisms with susceptibility to obesity

Autor:	Foad Ghazizadeh, Sepideh Afshari-Moez, Nazila Alinaghian, Mansour Torab, Parvaneh Rahimi-Moghaddam
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	adiponectin obesity polymorphism visfatin Medicine
Zdroj:	International Journal of Preventive Medicine, Vol 14, Iss 1, Pp 115-115 (2023)
Druh dokumentu:	article
ISSN:	2008-7802 2008-8213
DOI:	10.4103/ijpvm.ijpvm_79_22
Popis:	Background: This study aimed to see whether the adiponectin 45T/G (rs2241766) and visfatin 4689G/T (rs2110385) gene polymorphisms in an Iranian population are linked to obesity and/or obesity-related traits in normal and obese individuals. Methods: 230 obese individuals and 169 healthy controls had their genomic DNA taken. The alleles and genotypes of the rs2241766 and rs2110385 polymorphisms were determined using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique. Results: Obese individuals had considerably greater frequencies of the G allele and GG genotypes of the rs2241766 polymorphism than healthy controls (35% vs 21%, Probability (P)
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/8e07e9d48cee4c6eacb190f32e21378f Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF