Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor

Autor: Niharika Patlolla, Pretty Ponnachan, Colin Jamora, Deepti Abbey
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Stem Cell Research, Vol 69, Iss , Pp 103112- (2023)
Druh dokumentu: article
ISSN: 1873-5061
DOI: 10.1016/j.scr.2023.103112
Popis: Human pluripotent stem cells serve as a robust model system to study disease pathogenesis in a dish and search for various targeted therapeutics. Collection of control lines from healthy individuals are essential for any study. Therefore, we have generated hiPSC line from a healthy male donor after episomal reprogramming of PBMCs. The generated line is pluripotent, had normal karyotype and has a potential of tri-lineage differentiation. The generated line would serve as control line of Asian origin from Indian population.
Databáze: Directory of Open Access Journals