| Autor: |
Mitchell Heuermann, Simon Bekker, Thomas Czeczok, Stacie Gregory, Arun Sharma |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Cancer Reports, Vol 5, Iss 7, Pp n/a-n/a (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2573-8348 |
| DOI: |
10.1002/cnr2.1537 |
| Popis: |
Abstract Background Tracheal chondrosarcoma is a rare malignancy, and formal treatment guidelines have not been established due to the lack of high quality studies. Best evidence at this time is limited to case reports. Aim Explore the role of surgical intervention, radiation therapy, and chemotherapy, and the long‐term outcomes for these interventions for tracheal chondrosarcoma. Methods and Results A literature search was performed using PubMed (1959–2020) and ResearchGate (1959–2020) using medical subject heading terms “tracheal chondrosarcoma” OR “trachea chondrosarcoma.” Additional reports were identified within reviewed articles and included for review. Articles pertaining to chondrosarcomas of the lung, bronchus, larynx, or other head and neck subsites were excluded. Cases of chondromas were excluded. Thirty‐five patients with tracheal chondrosarcoma were identified in the literature since 1959. Advanced age was significantly associated with recurrent or persistent disease (p = .003). The majority (77%) of cases were treated with open surgical resection, with an open approach and negative surgical margins being significantly associated with being disease‐free after treatment (p = .001 and p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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