Familial Mediterranean Fever: Current Approaches to Diagnosis and Treatment

Autor:	Mikhail M. Kostik, Olga V. Zhogova, Natalia V. Lagunova, Sergey V. Ivanovskiy, Oksana L. Kolobova, Larisa N. Melnikova
Jazyk:	English<br />Russian
Rok vydání:	2018
Předmět:	familial mediterranean fever periodic fever fever of unknown origin interleukin 1 colchicine anakinra canakinumab Pediatrics RJ1-570
Zdroj:	Вопросы современной педиатрии, Vol 17, Iss 5, Pp 371-380 (2018)
Druh dokumentu:	article
ISSN:	1682-5527 1682-5535
DOI:	10.15690/vsp.v17i5.1953
Popis:	Familial Mediterranean fever is a typical monogenic disease with an autosomal recessive inheritance pattern; caused by mutations in the MEFV gene, which encodes the pyrin protein. It is a relatively rare pathology in the practice of paediatricians and rheumatologists of the Russian Federation. The article provides up-to-date data on the disease prevalence, presents a complete clinical picture of the auto-inflammatory syndrome, discusses diagnostic criteria and methods for treating patients with familial Mediterranean fever.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/8decaa6a1006450cbc7f1f3250ef1d47 Zobrazit plný text záznamu View record in DOAJ