| Autor: |
SiJun Li, Chufeng He, Qi Feng, YiJiang Bai, Xianlin Liu, Jie Ling, Lingyun Mei, XueWen Wu, Yong Feng, Jian Song |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Stem Cell Research, Vol 64, Iss , Pp 102916- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1873-5061 |
| DOI: |
10.1016/j.scr.2022.102916 |
| Popis: |
The human induced pluripotent stem cell (iPSC) lines, CSUXHEi001-A and CSUXHEi002-A, were generated from peripheral blood mononuclear cells (PBMCs). The donors were couple and each of them has a heterozygous mutation in the SLC26A4 gene. It manifests in their children as Enlarged vestibular aqueduct (EVA). The use of iPSC will allow describing the early stages of hearing loss, which is undoubtedly relevant for identifying key stages of development at which phenotypic manifestations of mutations in the SLC26A4 gene are found. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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