| Autor: |
Yoshinobu Kariya, Midori Oyama, Takato Suzuki, Yukiko Kariya |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2399-3642 |
| DOI: |
10.1038/s42003-021-02003-6 |
| Popis: |
Kariya, Oyama et al. propose that αvβ3 can drive a partial EMT phenotype characterized by maintained E-cadherin expression and upregulation of mesenchymal markers. This hybrid EMT state is independent of TGF-β1 signaling and characterised by increased migration, invasion, tumor cell proliferation, stemness and metastatic capacity. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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