Utility of simultaneous assessment of bone marrow aspirates and trephine biopsy sections in various haematological disorders

Autor: Vandana Puri, Pooja Sharma, Mrinalini Kotru, Meera Sikka, Satendra Sharma
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Iraqi Journal of Hematology, Vol 7, Iss 1, Pp 26-32 (2018)
Druh dokumentu: article
ISSN: 2072-8069
DOI: 10.4103/ijh.ijh_33_17
Popis: Background: Bone marrow examination is crucial diagnostic modality for evaluation of various hematological and nonhematological disorders. However, marrow aspirate smears and biopsy sections, even though performed simultaneously, are often assessed at different points of time due to different processing methods. This sometimes results in discordance in diagnosis which adds to the diagnostic dilemma and delays the treatment. aim: This study aims to compare the diagnostic accuracy and the rate of concordance between the two modalities of bone marrow examination. Materials and Methods: Three hundred simultaneously performed bone marrow aspirates and BM trephine biopsies were retrospectively analyzed over a period of 1 year. The presence or absence of concordance was recorded. The reasons for inconclusive reports were also recorded. The concordance rates for different hematological disorders were calculated and recorded as high for >80%, moderate for 50%–80%, and low for
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