Phytochemical screening and evaluation of the antimicrobial and antioxidant activities of Ferula caspica M. Bieb. extracts
| Autor: | Cigdem Kahraman, Gulacti Topcu, Erdal Bedir, I. Irem Tatli, Melike Ekizoglu, Zeliha S. Akdemir |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Saudi Pharmaceutical Journal, Vol 27, Iss 4, Pp 525-531 (2019) |
| Druh dokumentu: | article |
| ISSN: | 1319-0164 76504948 |
| DOI: | 10.1016/j.jsps.2019.01.016 |
| Popis: | Chloroform, ethyl acetate and methanol extracts from the aerial parts of Ferula caspica M. Bieb. were tested for their antioxidant capacities by CUPRAC, ABTS, FRAP, Folin–Ciocalteu and aluminum chloride methods and for antimicrobial activities by the broth microdilution method. Chloroform and ethyl acetate extracts showed the highest antioxidant capacity and antimicrobial activity. Three known sesquiterpene derivatives; 1-(2′,4′-dihydroxyphenyl)-3,7,11-trimethyl-3-vinyl-6(E),10-dodecadien-1-one (1), 2,3-dihydro-7-hydroxy-2,3-dimethyl-2-[4′,8′-dimethyl-3′,7′-nonadienyl]-furo[3,2,c]coumarin (2), 2,3-dihydro-7-hydroxy-2,3-dimethyl-3-[4′,8′-dimethyl-3′,7′-nonadienyl]-furo[3,2,c]coumarin(3); phenylpropanoid; laserine/2-epilaserine (4/5) and steroid mixtures; stigmasterol and β-sitosterol (6/7) were isolated from chloroform extract; three known flavonoids; kaempferol-3-O-β-glucopyranoside (8), kaempferol-3-O-α-rhamnopyranoside (9), quercetin-3-O-β-glucopyranoside (10), and one benzoic acid derivative; 2,4-dihydroxybenzoic acid (11) were isolated from the ethyl acetate extract. The structures were elucidated by spectroscopic methods. Keywords: Ferula caspica, Constituents, NMR, Antimicrobial, Antioxidant |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|