Influence of the degree of conversion and Bis-GMA residues of bulk fill resins on tissue toxicity in an subcutaneous model in rats
Autor: | Liliana Barreto Girão, Joyce Ohana de Lima Martins, José Vitor Mota Lemos, Marcílio Rodrigues Pinto, Juliana Paiva Marques Lima Rolim, Francisco Cláudio Fernandes Alves e Silva, Vicente de Paulo Aragão Saboia, Fabrício Bitu Sousa, Paulo Goberlânio de Barros Silva |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: | |
Zdroj: | Journal of Applied Biomaterials & Functional Materials, Vol 18 (2020) |
Druh dokumentu: | article |
ISSN: | 2280-8000 22808000 |
DOI: | 10.1177/2280800020947330 |
Popis: | Aim: To analyse the influence of the degree of conversion (DC) and light curing residues of different bulk fills (BFs) composites on the inflammatory profile in the subcutaneous tissue of rats. Materials and methods: Resin disks of BF-resins and their active conventional resins (CR; 3M®, Ivoclar®, and Kerr®) were light-cured at 2 mm (BF-superficial) and 4 mm (BF-deep) thicknesses and analyzed by infrared spectroscopy (FTIR; n = 3/group; DC and light curing residues). Then, the disks were implanted in four quadrants in the subcutaneous tissue of Wistar rats (sham, CR, BF-superficial and RF-deep), and after 7, 14, and 28 days, the animals ( n = 6/day) were euthanized for histological analysis of the intensity of the inflammatory process (scores 0–3). Kruskal–Wallis/Dunn and ANOVA/Bonferroni tests were used ( p |
Databáze: | Directory of Open Access Journals |
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