Impact of Nonlordotic Sagittal Alignment on Short-term Outcomes of Cervical Disc Replacement

Autor: Jung Kee Mok, Avani S. Vaishnav, Chirag Chaudhary, R. Kiran Alluri, Ryan Lee, Hikari Urakawa, Kosuke Sato, Darren A. Chen, Catherine Himo Gang, Russel Huang, Todd J. Albert, Sheeraz A. Qureshi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Neurospine, Vol 17, Iss 3, Pp 588-602 (2020)
Druh dokumentu: article
ISSN: 2586-6583
2586-6591
DOI: 10.14245/ns.2040398.199
Popis: Objective To evaluate outcomes of cervical disc replacement (CDR) in patients with nonlordotic alignment. Methods Patients who underwent CDR were retrospectively reviewed and divided into 3 cohorts: (1) neutral/lordotic segmental and C2–7 Cobb angle (L), (2) nonlordotic segmental Cobb angle, lordotic C2–7 Cobb angle (NL-S), and (3) nonlordotic segmental and C2–7 Cobb angle (NL-SC). Radiographic and patient-reported outcomes (PROMs) were compared. Results One-hundred five patients were included (L: 37, NL-S: 30, NL-SC: 38). A significant gain in segmental lordosis was seen in all cohorts at < 6 months (L: -1.90° [p = 0.007]; NL-S: -5.16° [p < 0.0001]; NL-SC: -6.00° [p < 0.0001]) and ≥ 6 months (L: -2.07° [p = 0.031; NL-S: -6.04° [p < 0.0001]; NL-SC: -6.74° [p < 0.0001]), with greater lordosis generated in preoperatively nonlordotic cohorts (p < 0.0001). C2–7 lordosis improved in the preoperatively nonlordotic cohort (NL-SC: 8.04°) at follow-up of < 6 months (-4.15°, p=0.003) and ≥ 6 months (-6.40°, p=0.003), but not enough to create lordotic alignment (< 6 months: 3.89°; ≥ 6 months: 4.06°). All cohorts showed improvement in Neck Disability Index, visual analogue scale (VAS) neck, and VAS arm, without significant difference among groups in the amount of improvement (≥ 6-month PROMs follow-up=69%). Conclusion In patients without major kyphotic deformity, CDR has the potential to generate and maintain lordosis and improve PROMs in the short-term, and can be an effective treatment option for patients with nonlordotic alignment.
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