Community-acquired pneumonia in hospitalised patients: changes in aetiology, clinical presentation, and severity outcomes in a 10-year period

Autor: Júlia Sellarès-Nadal, Joaquín Burgos, María Teresa Martín-Gómez, Andrés Antón, Roger Sordé, Daniel Romero-Herrero, Pau Bosch-Nicolau, Anna Falcó-Roget, Cristina Kirkegaard, Dolors Rodríguez-Pardo, Oscar Len, Vicenç Falcó
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Annals of Medicine, Vol 54, Iss 1, Pp 3052-3059 (2022)
Druh dokumentu: article
ISSN: 07853890
1365-2060
0785-3890
DOI: 10.1080/07853890.2022.2138529
Popis: Background and objective Community-acquired pneumonia (CAP) is a frequent cause of hospitalisation. Several factors, such as pandemics, vaccines and globalisation may lead to changes in epidemiology, clinical presentation, and outcomes of CAP, which oblige to a constant actualisation. We performed this study to analyse how these factors have evolved over a 10-year period.Materials and methods Patients diagnosed with CAP for two 1-year periods that were 10 years apart (2007–2008 and 2017–2018) were included. We compared microbiological information, clinical data and evolutive outcomes in the two periods. A mortality analysis was performed.Results 1043 patients were included: 452 during the first period (2007- 2008), and 591 during the second period (2017–2018). Bacterial aetiology did not change during the 10-year period, besides a slight increase in Staphylococcus aureus (0.9% vs 2.9%, p = 0.026). There was a decline in the proportion of bacteraemia in the second period (14.8% vs 9.6%, p = 0.012). The incidence of complicated pleural effusion and septic shock declined too (6.4% vs 3.6%, p = 0.04 and 15.5% vs 6.3%, p
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