| Autor: |
Ibrahim Alsadhan, MBBS, Shahad Alruwashid, MBBS, Maram Alhamad, MBBS, Sarah Alajmi, MBBS, Sara Alshehri, MBBS, Eman Alfadhli, MD, Aishah Ekhzaimy, MD |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Current Therapeutic Research, Vol 93, Iss , Pp 100609- (2020) |
| Druh dokumentu: |
article |
| ISSN: |
0011-393X |
| DOI: |
10.1016/j.curtheres.2020.100609 |
| Popis: |
ABSTRACT: Background: Coronavirus disease 2019 (COVID-19) has evolved into a devastating pandemic since December 2019. Saudi Arabia's first case was reported in March 2020. Subsequently, some 220,000 cases and 2000 deaths were recorded through July 2020. COVID-19 infection aggravates glycemic control and provokes acute hyperglycemic crises, according to some reports. We made the same observations in some of our patients diagnosed with COVID-19. However, we are unaware of any reported cases of diabetic ketoacidosis (DKA) among COVID-19 patients in Saudi Arabia. Objective: Highlighting the significance of hyperglycemia on COVID-19 patient outcomes. Methods: Five patients with DKA were admitted and diagnosed with COVID-19 based on real-time reverse transcription-polymerase chain reaction assays. Electronic medical records were reviewed and informed consent was obtained before reporting the index cases. Results: Five patients presenting with DKA complicating a concurrent COVID-19 infection were reported. Three were known to have preexisting diabetes and 2 had newly diagnosed diabetes based on significantly elevated glycated hemoglobin levels at admission. Four recovered and were discharged to their homes and 1 had a complicated course and died. Conclusions: Our cases demonstrate that COVID-19 infection can trigger DKA. DKA can occur among patients who are known to have diabetes mellitus or appears as a first presentation. Clinicians should be extremely careful in checking for admission hyperglycemia and closely monitor respiratory status during fluid resuscitation of COVID–19-related DKA. (Curr Ther Res Clin Exp. 2020; 81:XXX–XXX) |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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