Joint effect of atrial fibrillation and obesity on mortality in critically ill patients

Autor: Hong-Da Zhang, Lei Ding, Li-Jie Mi, Ai-Kai Zhang, Yuan-Dong Liu, Fu-Hua Peng, Xin-Xin Yan, Yu-Jing Shen, Min Tang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Diabetology & Metabolic Syndrome, Vol 16, Iss 1, Pp 1-11 (2024)
Druh dokumentu: article
ISSN: 1758-5996
DOI: 10.1186/s13098-024-01407-8
Popis: Abstract Background The interplay between atrial fibrillation (AF) and obesity on mortality in critically ill patients warrants detailed exploration, given their individual impacts on patient prognosis. This study aimed to assess the associations between AF, obesity, and 1-year mortality in a critically ill population. Methods Utilizing data from the Medical Information Mart for Intensive Care (MIMIC)-IV database, we conducted a retrospective analysis of adult patients admitted to the intensive care unit. The primary endpoint was 1-year mortality, analyzed through Cox regression with hazard ratio (HR) and Kaplan-Meier survival methods. Results The study included 25,654 patients (median age 67.0 years, 40.6% female), with 39.0% having AF and 36.1% being obese. Multivariate COX regression analysis revealed that AF was associated with a 14.7% increase in the risk of 1-year mortality (p
Databáze: Directory of Open Access Journals
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