Distinct homeostatic modulations stabilize reduced postsynaptic receptivity in response to presynaptic DLK signaling

Autor: Pragya Goel, Dion Dickman
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-018-04270-0
Popis: Dual leucine zipper kinase (DLK) activates an intrinsic neuronal response to injury and is also implicated in neurodegeneration. Here, Goel and Dickman characterize how postsynaptic targets adapt to presynaptic DLK signaling through a downregulation of synaptic strength.
Databáze: Directory of Open Access Journals