Whole chromosome loss and genomic instability in mouse embryos after CRISPR-Cas9 genome editing
| Autor: | Stamatis Papathanasiou, Styliani Markoulaki, Logan J. Blaine, Mitchell L. Leibowitz, Cheng-Zhong Zhang, Rudolf Jaenisch, David Pellman |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-021-26097-y |
| Popis: | A possible undesired outcome of CRISPR-Cas9 germline editing is unwanted karyotype alterations. Here the authors track aberrations through three divisions of embryonic development following Cas9 editing. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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